سمینار مقدماتی نسخههای خطی (اولین: 1 - 2 خرداد 1379: تهران)
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Dmd058602 1379..1391
Cytochrome P450 (P450) induction is often considered a liability in drug development. Using calibration curve–based approaches, we assessed the induction parameters R3 (a term indicating the amount of P450 induction in the liver, expressed as a ratio between 0 and 1), relative induction score, Cmax/EC50, and area under the curve (AUC)/F2 (the concentration causing 2-fold increase from baseline ...
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volume 11 issue 3
pages 109- 119
publication date 2000-11-21
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